Office of Human Research Protections (OHRP)
This federal agency oversees all registered Institutional Review Boards (IRBs).
- OHRP Home Page
- 45 CFR 46- Code of Federal Regulations Pre- 2018 - This is the older version of the regulations, which will only apply to research reviewed and approved prior to January 21, 2019 and not transitioned to the revised regulations on or after that date.
- 45 CFR 46- Code of Federal Regulations- 2018 version- This is the revised regulations (Common Rule), which became effective January 21, 2019. All research reviewed and approved on or afterJanuary 21, 2019 must be fully compliant with these regulations.
- Categories of Research That May be Reviewed by the IRB Through Expedited Review
- OHRP Guidance on topics related to Human subject research. Topics include informed consent, vulnerable populations, institutional issues, protocol review, biological material and data.
- OHRP Frequently Asked Questions (FAQs) on specific topics related to human subject research. Topics include 45 CFR 46, the assurance process, children in research, the consent process, exempt research, research with prisoners, investigator responsibilities, and quality improvement activities.
- OHRP Check lists and Decisions Trees - Provides decision trees for determining whether your project or activity is research, involves human subjects, meets the criteria for exemption, expedited, or full review, and which exempt or expedited categories to which your research belongs:
- OHRP IRB Guidebook - This resource is now archived on the OHRP website, but is still useful for explaining key concepts and how to apply the federal regulations.
DePaul Guidelines
Ethical Codes and Standards